ABC General Hospital Shocker

It’s the end of an era in Port Charles — and fans are not ready.

In an emotional twist that few saw coming, Drew Cain has made his final appearance on General Hospital, with Cameron Mathison’s last scene officially aired this week. After months of rumors swirling around Mathison’s status with the show, GH has confirmed that this was his final episode… and it was a tearjerker.

Here’s everything we know about Drew’s heartbreaking goodbye, what it means for the future of GH, and what Cameron Mathison had to say about leaving.

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 Drew’s Final Scene: A Farewell Filled With Pain

In Tuesday’s episode, fans watched through tears as Drew Cain shared one final moment with Carly Spencer, holding her hand from his hospital bed after surviving a second gunshot wound — only to make a quiet, devastating choice.

Knowing that his presence continues to bring danger to those he loves — and haunted by his involvement with Pikeman and the WSB — Drew told Carly:

“I can’t stay and keep putting you and Scout in the line of fire. I have to go… for good this time.”

He then recorded a video message for Scout, asking her to grow up brave, strong, and kind — much like her mom and grandmother. The camera lingered on his face as he blinked back tears… and then he was gone.

No hospital monitors flatlined. No explosion. No dramatic gunfire. Just a quiet, painful goodbye.

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 Cameron Mathison: Officially Out at GH

After much speculation, ABC has confirmed that this episode marked Cameron Mathison’s final appearance as Drew Cain. His exit had been kept tightly under wraps, and insiders say the decision was “mutual and respectful.”

Mathison, who joined General Hospital in 2021, brought a grounded, layered performance to the role of Drew, stepping into the character’s shoes post-memory-loss storyline. His departure closes another chapter in the Cain family saga — and leaves Carly, Scout, and Sam reeling.

➤ Mathison’s Statement:

In a heartfelt post on social media, Mathison shared:

“Thank you to the incredible cast, crew, and fans of GH. It’s been an honor to play Drew Cain, and I’m grateful for every moment. New adventures ahead, but I’ll always have a place in my heart for Port Charles.”

He did not say if he’d return in the future — but left the door open.

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 What Happens to Drew Now?

Spoilers suggest Drew is not dead, but has disappeared off the grid — possibly working undercover to take down Pikeman once and for all. Whether the character will be recast down the road or remain out of sight is unclear.

This leaves several loose ends:

What will Carly do now that she’s lost another man she loves?

How will Scout process her father’s absence… again?

And will Jason, Sam, or Sonny pick up the pieces where Drew left off?

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 Final Thoughts

Drew Cain’s final goodbye wasn’t explosive — it was quiet, emotional, and painfully real. That’s what made it hit even harder. GH chose to give Drew the kind of exit that mirrors real life: full of hard choices, personal sacrifice, and love that lingers even after goodbye.

And for fans of Cameron Mathison? His chapter in Port Charles may be over — but his legacy lives on.